diff --git a/plugins/history-substring-search/history-substring-search.zsh b/plugins/history-substring-search/history-substring-search.zsh
index 9f0e0b0d5..db516f580 100644
--- a/plugins/history-substring-search/history-substring-search.zsh
+++ b/plugins/history-substring-search/history-substring-search.zsh
@@ -45,7 +45,14 @@
 
 : ${HISTORY_SUBSTRING_SEARCH_HIGHLIGHT_FOUND='bg=magenta,fg=white,bold'}
 : ${HISTORY_SUBSTRING_SEARCH_HIGHLIGHT_NOT_FOUND='bg=red,fg=white,bold'}
-: ${HISTORY_SUBSTRING_SEARCH_GLOBBING_FLAGS='i'}
+
+# Respect CASE_SENSITIVE setting for case sensitivity
+if [[ "$CASE_SENSITIVE" = true ]]; then
+  : ${HISTORY_SUBSTRING_SEARCH_GLOBBING_FLAGS=''}
+else
+  : ${HISTORY_SUBSTRING_SEARCH_GLOBBING_FLAGS='i'}
+fi
+
 : ${HISTORY_SUBSTRING_SEARCH_ENSURE_UNIQUE=''}
 : ${HISTORY_SUBSTRING_SEARCH_FUZZY=''}
 : ${HISTORY_SUBSTRING_SEARCH_PREFIXED=''}